贝尔纳卡桑

CAS号：273404-37-8

货号：BCP02893

中文名：贝尔纳卡桑

英文名：Belnacasan

中文别名：-

英文别名：VX-765;VX 765;VX765

分子式：C24H33ClN4O6

分子量：508.99

纯度：98%

信号通路：Protease/Metabolic Enzyme Apoptosis Pathway 

靶点：Caspase 

配送：惯例下常温包邮（限中国大陆地区）

产品描述：Belnacasan (VX-765) is an orally bioactive proagent of VRT-043198, which is a potent and selective inhibitor of IL-converting enzyme (ICE)/caspase-1 with Kis of 0.8 nM and less than 0.6 nM for caspase-1 and caspase-4, respectively. Belnacasan (VX-765) inhibits the release of LPS-induced IL-1β and IL-18 by human PBMCs with an IC50 of ~0.7 μM.