依伐卡托

CAS号：873054-44-5

货号：BCP01857

中文名：依伐卡托

英文名：Ivacaftor

中文别名：依法卡托;艾伐卡托

英文别名：VX-770;VX770;VX 770;Kalydeco

分子式：C24H28N2O3

分子量：392.49

纯度：98%

信号通路：Ion Channel/Membrane Transporter 

靶点：CFTR 

配送：惯例下常温包邮（限中国大陆地区）

产品描述：Ivacaftor, also known as VX-770, is a drug used to treat cystic fibrosis in people with certain mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene, who account for 4–5% cases of cystic fibrosis, and is included in a combination drug, lumacaftor/ivacaftor, which is used to treat people with cystic fibrosis who have the F508del mutation in CFTR. Ivacaftor is a "potentiator" of CFTR, meaning it increases the probability that the defective channel will be open and allow chloride ions pass through the channel pore.