AY 9944

CAS号：366-93-8

货号：BCP49752

中文名：AY 9944

英文名：AY 9944

中文别名：-

英文别名：-

分子式：C22H30Cl4N2

分子量：464.3

纯度：98%

信号通路：Others Pathway 

靶点：Others 

配送：惯例下常温包邮（限中国大陆地区）

产品描述：AY 9944 is a specific cholesterol biosynthesis inhibitor. AY 9944 inhibits the 7-dehydro cholesterol Δ7-reductase (DHCR7) enzyme with an IC50 of 13 nM. AY 9944 causes hypocholesterolemia and accumulation of 7DHC. At high doses, AY 9944 inhibits also in cultured embryos sterol Δ7-Δ8 isomerase, which causes the accumulation of cholest-8-en-3β-ol.