产品详情

索喹替尼

CAS号:2226636-04-8

货号:BCP49733

中文名:索喹替尼

英文名:Soquelitinib

中文别名:-

英文别名:CPI-818;CPI 818;CPI818

分子式:C25H30N4O4S2

分子量:514.66

纯度:98%

信号通路:Others Pathway 

靶点:Others 

配送:惯例下常温包邮(限中国大陆地区)

产品描述:Soquelitinib (CPI-818) is an orally active and highly selective covalent interleukin-2-inducible kinase (ITK) inhibitor. Soquelitinib is active in six different models of T cell-mediated inflammatory and immune disease, including acute and chronic asthma, pulmonary fibrosis, systemic sclerosis (scleroderma), psoriasis, and acute graft versus host disease with Th2 cytokine product inhibition. Soquelitinib increases tumor infiltration of normal CD8+ cells that possess enhanced T effector function.

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